Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Genomewide Association Study on Fallible Behavior of Accident-Repeated Drivers in China
Chinese National Center of Engineering and Technology for Vehicle Driving Safety, Anhui Sanlian University, China.
Chinese National Center of Engineering and Technology for Vehicle Driving Safety, Anhui Sanlian University, China.
Chinese National Center of Engineering and Technology for Vehicle Driving Safety, Anhui Sanlian University, China.
Chinese National Center of Engineering and Technology for Vehicle Driving Safety, Anhui Sanlian University, China.
2013 (English)In: Proceedings of the 16th International Conference Road Safety on Four Continents: Beijing, China. 15-17 May 2013, Linköping: Statens väg- och transportforskningsinstitut, 2013Conference paper, Published paper (Other academic)
Abstract [en]

Driving behavior of a driver is closely related to traffic accidents, and is controlled by nervous system. Gene expression in the nervous cells may indirectly affect people's behavior. In order to explore genetic basis of fallible behavior of the accident-repeated drivers, in accordance with the Chinese national standard "Physical qualifications for automobile drivers and their test protocol" (GB18463-2001), these drivers whose indexes were all abnormal were chose as candidates of case, and those whose indexes were all normal were chose as candidates of control. A total of 232 matching pairs of drivers were selected. We chose above case candidates who had three or more accidents at the level of more than equal-responsibility within 5 consecutive years (2005-2009) as case group. The control candidates who did not have liability for accidents over the same years (2005-2009) as control group, 179 matching pairs of drivers has been chosen as sample. GWAS (Genome-wide association study) are applied to 179 pairs of matching samples on fallible behavior of drivers. The result showed that 31 SNPs loci in 3 linked genes (SMAD5,TRPC7(P<10-4)and CBLN4 (P<10-5) ) are associated with fallible behavior of drivers .The current study suggested for the first time the potential association between the fallible behavior and the potential susceptible genes.

Place, publisher, year, edition, pages
Linköping: Statens väg- och transportforskningsinstitut, 2013.
Keyword [en]
Accident proneness, Medical aspects
National Category
Medical Genetics
Research subject
80 Road: Traffic safety and accidents, 84 Road: Road users; X RSXC
Identifiers
URN: urn:nbn:se:vti:diva-7347OAI: oai:DiVA.org:vti-7347DiVA: diva2:759142
Conference
16th International Conference Road Safety on Four Continents. Beijing, China (RS4C 2013). 15-17 May 2013
Available from: 2014-10-29 Created: 2014-10-29 Last updated: 2014-10-29Bibliographically approved

Open Access in DiVA

fulltext(553 kB)120 downloads
File information
File name FULLTEXT01.pdfFile size 553 kBChecksum SHA-512
d5e766ee7f8e3bcceb596a44aaa29b49628cce328429dd37a627dbd9a46ba616fab5b37a62473b1301347a71e4f05a8cf719e9fe5df9b3ee1a1bd772e855099b
Type fulltextMimetype application/pdf

Medical Genetics

Search outside of DiVA

GoogleGoogle Scholar
Total: 120 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Total: 65 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf