The legal reference in the field of driving license in the EU is currently the 2006/126/EC Directive, which stipulates that driving licenses shall be granted only to those who meet medical requirements and pass a driving test. This Directive has recently been updated with the Directive EU 2015/653. Actually, there is a lack of knowledge in the application of validated procedures for assessing (potential) drivers of adapted vehicles. The objective of this paper it is to present experimental results of driving assessment procedures developed for assessing drivers with impairments –both motor and sensory-. This assessment is based on performing a series of practical tests in a static test rig and a low-cost driving simulator.